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Cyclohexanecarboxamide, N-[2-(1-piperazinyl)ethyl]- synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 1 h / 20 °C
2: hydrogenchloride; hydrogen; acetic acid / palladium 10% on activated carbon / water / 3 h / 60 °C / 1551.49 Torr

References:

WO2011/150183,2011,A1