Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-4,6-dimethoxy-6'-methyl-2'-(phenylmethoxy)-, (1'S,6'R)- synthesis
- Product Name:Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-4,6-dimethoxy-6'-methyl-2'-(phenylmethoxy)-, (1'S,6'R)-
- CAS Number:888042-13-5
- Molecular formula:C23H21ClO6
- Molecular Weight:428.86
![2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione](/CAS/GIF/26881-56-1.gif)
Yield:888042-13-5 55%
Reaction Conditions:
with 1,8-diazabicyclo[5.4.0]undec-7-ene in 1,4-dioxane at 100; for 12 h;
References:
R?nnest, Mads H.;Rebacz, Blanka;Markworth, Lene;Terp, Anette H.;Larsen, Thomas O.;Kr?mer, Alwin;Clausen, Mads H. [Journal of Medicinal Chemistry,2009,vol. 52,# 10,p. 3342 - 3347] Location in patent:supporting information; experimental part
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