Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)- synthesis
- Product Name:Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2R)-
- CAS Number:908303-26-4
- Molecular formula:C24H23F12NOSi
- Molecular Weight:597.51
27607-77-8
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948595-00-4
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908303-26-4
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Yield: 81%
Reaction Conditions:
with triethylamine in dichloromethane at 0; for 1 h;Inert atmosphere;
References:
Lin, Qiyan;Meloni, David;Pan, Yongchun;Xia, Michael;Rodgers, James;Shepard, Stacey;Li, Mei;Galya, Laurine;Metcalf, Brian;Yue, Tai-N;Liu, Pingli;Zhou, Jiacheng [Organic Letters,2009,vol. 11,# 9,p. 1999 - 2002] Location in patent:supporting information; experimental part