N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine synthesis
- Product Name:N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
- CAS Number:912569-84-7
- Molecular formula:C36H50ClN3O10S
- Molecular Weight:752.32
139504-50-0
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Yield:912569-84-7 72%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide at 20; for 1 h;Inert atmosphere;
References:
Widdison, Wayne;Wilhelm, Sharon;Veale, Karen;Costoplus, Juliet;Jones, Gregory;Audette, Charlene;Leece, Barbara;Bartle, Laura;Kovtun, Yelena;Chari, Ravi [Molecular Pharmaceutics,2015,vol. 12,# 6,p. 1762 - 1773]