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1H-Pyrrole-1-carboxylic acid, 2-(2,3-dihydro-3-oxo-1H-isoindol-4-yl)-, 1,1-diMethylethyl ester synthesis

1synthesis methods
200049-46-3 Synthesis
7-Bromo-2,3-dihydro-isoindol-1-one

200049-46-3
91 suppliers
$22.00/100mg

1H-Pyrrole-1-carboxylic acid, 2-(2,3-dihydro-3-oxo-1H-isoindol-4-yl)-, 1,1-diMethylethyl ester

935269-07-1
12 suppliers
inquiry

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Yield:935269-07-1 17%

Reaction Conditions:

with palladium diacetate;sodium carbonate;tris-(o-tolyl)phosphine in water;N,N-dimethyl-formamide;Suzuki coupling;

References:

Hughes, Terry V.;Emanuel, Stuart L.;O'Grady, Harold R.;Connolly, Peter J.;Rugg, Catherine;Fuentes-Pesquera, Angel R.;Karnachi, Prabha;Alexander, Richard;Middleton, Steven A. [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 18,p. 5130 - 5133] Location in patent:scheme or table