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3-AMINO-2,2,5,7-TETRAMETHYL-2,3-DIHYDRO-1H-INDEN-4-OL synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: NH3 / methanol / 10 h / 100 °C
2: H2 / 5percent Pd/C / ethyl acetate / 4 h / 760 Torr

References:

Oshiro, Yasuo;Sakurai, Youji;Tanaka, Tatsuyoshi;Ueda, Hiraki;Kikuchi, Tetsuro;Tottori, Katura [Journal of Medicinal Chemistry,1991,vol. 34,# 7,p. 2004 - 2013]