ChemicalBook CAS DataBase List Afatinib Impurity 77

Afatinib Impurity 77 synthesis

2synthesis methods

67-63-0 Synthesis

Yield:26404-20-6 80%

Reaction Conditions:

in dichloromethane at 0 - 20; for 2.33333 h;

References:

Donnelly, Kian;Baumann, Marcus [Chemical Communications,2021,vol. 57,# 23,p. 2871 - 2874] Location in patent:supporting information

615-81-6 Synthesis

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