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AKOS B018337 synthesis

1synthesis methods
-

Yield: 75%

Reaction Conditions:

with ammonium acetate in toluene at 110; for 12 h;

References:

Russell, Angela J.;Westwood, Isaac M.;Crawford, Matthew H.J.;Robinson, James;Kawamura, Akane;Redfield, Christina;Laurieri, Nicola;Lowe, Edward D.;Davies, Stephen G.;Sim, Edith [Bioorganic and Medicinal Chemistry,2009,vol. 17,# 2,p. 905 - 918] Location in patent:experimental part

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