AKOS BB-7590 synthesis
- Product Name:AKOS BB-7590
- CAS Number:917747-10-5
- Molecular formula:C12H9ClN2
- Molecular Weight:216.67
482639-32-7
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$134.00/1g
917747-10-5
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$200.00/500mg
Yield:917747-10-5 93%
Reaction Conditions:
Stage #1: 2-chloro-5,7-dimethylquinoline-3-carbaldehydewith hydroxylamine hydrochloride;triethylamine in ethanol; for 3 h;Reflux;
Stage #2: with hydrogenchloride in water;
Stage #3: with thionyl chloride in benzene; for 4 h;Inert atmosphere;Reflux;
References:
Phuan, Puay-Wah;Yang, Baoxue;Knapp, John M.;Wood, Alex B.;Lukacs, Gergely L.;Kurth, Mark J.;Verkman, Alan S. [Molecular Pharmacology,2011,vol. 80,# 4,p. 683 - 693] Location in patent:experimental part
2050-45-5
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917747-10-5
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$200.00/500mg
108-69-0
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$9.00/1g
917747-10-5
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$200.00/500mg
![N-[(2-chloro-5,7-dimethylquinolin-3-yl)methylidene]hydroxylamine](/CAS/20180601/GIF/1356485-81-8.gif)
1356485-81-8
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917747-10-5
21 suppliers
$200.00/500mg