BenzenaMine, 4-broMo-2-ethyl-6-Methyl- synthesis

Yield:70598-49-1 100%

Reaction Conditions:

with N-Bromosuccinimide in N,N-dimethyl-formamide at 0 - 20;

References:

Freeman-Cook, Kevin D.;Amor, Paul;Bader, Scott;Buzon, Leanne M.;Coffey, Steven B.;Corbett, Jeffrey W.;Dirico, Kenneth J.;Doran, Shawn D.;Elliott, Richard L.;Esler, William;Guzman-Perez, Angel;Henegar, Kevin E.;Houser, Janet A.;Jones, Christopher S.;Limberakis, Chris;Loomis, Katherine;McPherson, Kirk;Murdande, Sharad;Nelson, Kendra L.;Phillion, Dennis;Pierce, Betsy S.;Song, Wei;Sugarman, Eliot;Tapley, Susan;Tu, Meihua;Zhao, Zhengrong [Journal of Medicinal Chemistry,2012,vol. 55,# 2,p. 935 - 942] Location in patent:supporting information; experimental part