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197178-54-4

Benzenepentanoic acid, 3,5-dimethoxy-, ethyl ester synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: NaH / tetrahydrofuran / 15 h
1.2: 50 percent / tetrahydrofuran / 12 h / 20 °C
2.1: 85 percent / H2 / Pd/C; Pd(OH)2 / methanol / 16.5 h

References:

Qi, Longwu;Yamamoto, Noboru;Meijler, Michael M.;Altobell III, Laurence J.;Koob, George F.;Wirsching, Peter;Janda, Kim D. [Journal of Medicinal Chemistry,2005,vol. 48,# 23,p. 7389 - 7399]