Benzoyl isocyanate, 4-methyl- (9CI) synthesis
- Product Name:Benzoyl isocyanate, 4-methyl- (9CI)
- CAS Number:5843-46-9
- Molecular formula:C9H7NO2
- Molecular Weight:161.16
Yield:5843-46-9 88%
Reaction Conditions:
with tin(IV) chloride;toluene-4-sulfonic acid in toluene at 50 - 60; for 9 h;
Steps:
4 Example 4
Put 42.25g (0.65mol) sodium cyanate, 19.5g (0.07mol) tin tetrachloride, 9.75g p-toluenesulfonic acid and 200g toluene in the reaction kettle,The temperature was controlled at 50-55 ° C, and 77.7g (0.5mol) 4-methylbenzoyl chloride was added dropwise.After the dropwise addition, the temperature was raised to 60 ° C for 9 hours, and the solvent was distilled off under reduced pressure, Continue to distill under reduced pressure to obtain 71.5g 4-methylbenzoyl isocyanate, GC purity 99.9%, yield 88%.
References:
CN111004150,2020,A Location in patent:Paragraph 0027-0028
![Benzamide, N-[(dimethylamino)carbonyl]-4-methyl-N-(4-methylbenzoyl)-](/CAS/20210305/GIF/104825-41-4.gif)
99-94-5
603 suppliers
$9.00/1g
5843-46-9
6 suppliers
inquiry
874-60-2
411 suppliers
$10.00/5g
5843-46-9
6 suppliers
inquiry