bicyclo[3.2.1]octane-3-carboxylic acid synthesis

2synthesis methods

Yield:-

Steps:

Multi-step reaction with 2 steps
1: Na / xylene / Heating
2: (i) KOH, MeOH, (ii) (decarboxylation)

References:

Buchta,E.;Billenstein,S. [Justus Liebigs Annalen der Chemie,1966,vol. 692,p. 42 - 52]

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