BOC-(R)-3-AMINO-4-(2-METHYL-PHENYL)-BUTYRIC ACID synthesis

Yield:-

Steps:

Multi-step reaction with 3 steps
1: Et₃N / tetrahydrofuran
2: diethyl ether
3: aq. C₆H₅CO₂Ag / dioxane / 20 °C / sonication

References:

Xu, Jinyou;Ok, Hyun O.;Gonzalez, Edward J.;Colwell Jr., Lawrence F.;Habulihaz, Bahanu;He, Huaibing;Leiting, Barbara;Lyons, Kathryn A.;Marsilio, Frank;Patel, Reshma A.;Wu, Joseph K.;Thornberry, Nancy A.;Weber, Ann E.;Parmee, Emma R. [Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,# 18,p. 4759 - 4762]