CAY10566 synthesis
- Product Name:CAY10566
- CAS Number:944808-88-2
- Molecular formula:C18H17ClFN5O2
- Molecular Weight:389.81
3827-49-4
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$14.00/1g
944808-88-2
52 suppliers
$60.00/1mg
Yield:-
Steps:
Multi-step reaction with 5 steps
1: 51 percent / triphenylphosphine; di-tert-butyl azodicarboxylate / tetrahydrofuran / 2 h / 25 °C
2: 75 percent / [1,1'-bis(diphenylphosphino)ferrocene]PdCl2(II)*CH2Cl2 / 3 h / 100 °C / 10343.2 Torr
3: 95 percent / aq. NaOH / methanol / 3 h / 25 °C
4: 92 percent / O-benzotriazol-1-yl-N,N,N',N'-tetramethyluronium(1+)*BF4(1-); Et3N / dimethylformamide / 1 h / 25 °C / pH 6
5: 52 percent / POCl3 / 6 h / 100 °C
References:
Liu, Gang;Lynch, John K.;Freeman, Jennifer;Liu, Bo;Xin, Zhili;Zhao, Hongyu;Serby, Michael D.;Kym, Philip R.;Suhar, Tom S.;Smith, Harriet T.;Cao, Ning;Yang, Ruojing;Janis, Rich S.;Krauser, Joel A.;Cepa, Steven P.;Beno, David W. A.;Sham, Hing L.;Collins, Christine A.;Surowy, Teresa K.;Camp, Heidi S. [Journal of Medicinal Chemistry,2007,vol. 50,# 13,p. 3086 - 3100]
1000210-73-0
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944808-88-2
52 suppliers
$60.00/1mg
1000210-73-0
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944808-88-2
52 suppliers
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89937-26-8
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$50.00/1 g
944808-88-2
52 suppliers
$60.00/1mg
1000210-73-0
0 suppliers
inquiry
944808-88-2
52 suppliers
$60.00/1mg