ChemicalBook CAS DataBase List DBPR108

DBPR108 synthesis

1synthesis methods

Product Name:DBPR108
CAS Number:1186426-66-3
Molecular formula:C16H25FN4O2
Molecular Weight:324.39

2-Pyrrolidinecarbonitrile, 1-(2-bromoacetyl)-4-fluoro-, (2S,4S)-

426844-30-6
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3-amino-3-methyl-1-(1-pyrrolidinyl)-1-Butanone

1186426-99-2
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1186426-66-3
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Yield:-

Reaction Conditions:

with potassium carbonate in tetrahydrofuran

References:

Yeh, Teng-Kuang;Tsai, Ting-Yueh;Hsu, Tsu;Cheng, Jai-Hong;Chen, Xin;Song, Jen-Shin;Shy, Horng-Shing;Chiou, Mei-Chun;Chien, Chia-Hui;Tseng, Ya-Ju;Huang, Chung-Yu;Yeh, Kai-Chia;Huang, Yu-Lin;Huang, Chih-Hsiang;Huang, Yu-Wen;Wang, Min-Hsien;Tang, Hung-Kuan;Chao, Yu-Sheng;Chen, Chiung-Tong;Jiaang, Weir-Torn [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 12,p. 3596 - 3600] Location in patent:scheme or table

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