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ChemicalBook CAS DataBase List desmethylcyproheptadine

desmethylcyproheptadine synthesis

8synthesis methods
1-Piperidinecarboxylic acid, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-, ethyl ester

121138-82-7
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Yield:14051-46-8 92%

Reaction Conditions:

with potassium hydroxide in butan-1-ol; for 2 h;Heating;

References:

Iwasaki;Sakaguchi;Ohashi;Yamazaki;Ogawa;Yasuda;Koshinaka;Kato;Ito;Sawanishi [Chemical and Pharmaceutical Bulletin,1994,vol. 42,# 11,p. 2285 - 2290]