Diethyl 2-isopropyl-3-oxosuccinate synthesis

1synthesis methods

108-64-5 Synthesis

95-92-1 Synthesis

Yield:59916-75-5 61%

Reaction Conditions:

Stage #1: Ethyl isovaleratewith sodium hydride in tetrahydrofuran;deprotonation;
Stage #2: oxalic acid diethyl ester in tetrahydrofuran;Alkylation;

References:

Chiba, Akira;Arai, Noriko;Eguchi, Tadashi;Kakinuma, Katsumi [Chemistry Letters,1999,# 12,p. 1313 - 1314]

Diethyl 2-isopropyl-3-oxosuccinate Related Search:

Dimethyl maleate

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