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29548-92-3

β,β-difluoro-α-methyl-Benzeneethanol synthesis

3synthesis methods
2248-46-6 Synthesis
(ALPHA,ALPHA-DIFLUORO)PHENYLACETIC ACID ETHYL ESTER

2248-46-6
102 suppliers
$25.00/1g

β,β-difluoro-α-methyl-Benzeneethanol

29548-92-3
2 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: tetrahydrofuran; diethyl ether / 1 h / -60 °C / Inert atmosphere
2: sodium tetrahydroborate / methanol / 1 h / 0 °C / Inert atmosphere

References:

Hsieh, Min-Tsang;Lee, Kuo-Hsiung;Kuo, Sheng-Chu;Lin, Hui-Chang [Advanced Synthesis and Catalysis,2018,vol. 360,# 8,p. 1605 - 1610]