DiMethyl 4-(TrifluoroMethyl)phthalate synthesis
1synthesis methods
- Product Name:DiMethyl 4-(TrifluoroMethyl)phthalate
- CAS Number:728-47-2
- Molecular formula:C11H9F3O4
- Molecular Weight:262.18
Yield:728-47-2 78%
Reaction Conditions:
Stage #1: dimethyl acetylenedicarboxylate;(E)-1-ethoxy-3-trifluoromethyl-1,3-butadiene at 100; for 16 h;Diels-Alder cycloaddition;
Stage #2: with potassium carbonate in acetone; for 1 h;Heating;Further stages.;
References:
Volle, Jean-Noel;Schlosser, Manfred [European Journal of Organic Chemistry,2002,# 9,p. 1490 - 1492]