DL-MUSCONE synthesis

8synthesis methods

Product Name:DL-MUSCONE
CAS Number:956-82-1
Molecular formula:C16H30O
Molecular Weight:0

956-83-2
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956-82-1
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Yield:956-82-1 321.3 g

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in methanol at 20;

Steps:

2.4 (4) Preparation of 3-methylcyclopentadecanone (muskone):

Add crude 3-methylcyclopentadecenone to a 2L three-necked round bottom bottle,1L of methanol and 3.5g of 10% palladium on carbon,First replace the air in the kettle with nitrogen 5 times,Then replace the nitrogen in the kettle with hydrogen 3 times, and react at room temperature and normal pressure until the reaction is complete.The catalyst is recovered after filtration, and the solvent methanol is recovered from the filtrate at atmospheric pressure.Under reduced pressure distillation, 321.3g of pure 3-methylcyclopentadecanone (muskone) was obtained,The corresponding yield is 92.3%.

References:

CN107602363,2020,B Location in patent:Paragraph 0046; 0056-0058