(E)-3-(anthracen-9-yl)-1-phenylprop-2-en-1-one synthesis

Yield:1564-72-3 95%

Reaction Conditions:

with magnesium oxide nanoparticles synthesized using Trachyspermum ammi leaf extract in ethanol at 80; for 1 h;Claisen-Schmidt Condensation;Temperature;Time;

Steps:

2.5. General procedure for the synthesis of chalcone by Claisen-Schmidt reaction

General procedure: The 9-Acetylanthracene 0.22 g (0.001 mol) and benzaldehyde 0.106g (0.001 mol) were taken in a 50 ml round bottom (RB) flask, 10 ml of 50% ethanol was used as a solvent with 15 mg MgO NPs as a catalyst.The reaction mixture was stirred in an oil bath at 80 °C for 1 hr. The reaction progress was monitor by TLC method. After completing the reaction, reaction mixture was poured into ice-cold water to separate the product and catalyst (Scheme 1).

References:

Dabhane, Harshal;Ghotekar, Suresh;Jadhav, Ghanshyam;Kute, Sagar;Medhane, Vijay;Zate, Manohar [Inorganic Chemistry Communications,2022,vol. 138,art. no. 109270]