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Estafietin synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: m-chloroperbenzoic acid
2: HCl / tetrahydrofuran
3: epoxidation
4: 85 percent / SOCl2 / pyridine
5: Zn / 18 h / Ambient temperature

References:

Macaira, Lelio A.;Machado, F. Welbaneide L.;Garcia, Marcos;Rabi, Jaime A. [Tetrahedron Letters,1980,vol. 21,p. 773 - 776]