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ESTRONE-2,4,16,16-D4 synthesis

2synthesis methods
-

Yield:53866-34-5 95%

Reaction Conditions:

Stage #1: Estronewith trifluoroacetic acid-d1 for 0.166667 h;heating in a microwave oven;
Stage #2: with ethanol

References:

Kiuru, Paula S;W?h?l?, Kristiina [Tetrahedron Letters,2002,vol. 43,# 18,p. 3411 - 3412]