ethyl 3-[(3-chloropyridin-2-yl)amino]benzoate synthesis
1synthesis methods
- Product Name:ethyl 3-[(3-chloropyridin-2-yl)amino]benzoate
- CAS Number:1163681-48-8
- Molecular formula:C14H13ClN2O2
- Molecular Weight:276.72
Yield:1163681-48-8 85%
Reaction Conditions:
with palladium diacetate;potassium carbonate;2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl in toluene; for 18 h;Reflux;regioselective reaction;Buchwald-Hartwig reaction;
References:
Hostyn, Steven;Van Baelen, Gitte;Lemiere, Guy L. F.;Maes, Bert U. W. [Advanced Synthesis and Catalysis,2008,vol. 350,# 16,p. 2653 - 2660] Location in patent:supporting information; scheme or table