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ChemicalBook CAS DataBase List Cyclobutanecarboxylic acid, 3-amino-, hydrochloride, cis-
84182-59-2

Cyclobutanecarboxylic acid, 3-amino-, hydrochloride, cis- synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: 88 percent / pyridine / 336 h
2: 80 percent / NH4Br, NH3 / 144 h / Ambient temperature
3: 59 percent / NaN3 / methanol; H2O / 20 h / Heating
4: 81 percent / H2 / PtO2 / methanol / 6 h / Ambient temperature
5: 79 percent / HCl / H2O / 20 h / Heating

References:

Safanda;Sobotka [Collection of Czechoslovak Chemical Communications,1982,vol. 47,# 9,p. 2440 - 2447]

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