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ChemicalBook CAS DataBase List Indolicidin
140896-21-5

Indolicidin synthesis

1synthesis methods
71989-31-6 Synthesis
Fmoc-Pro-OH

71989-31-6
517 suppliers
$6.00/5g

71989-23-6 Synthesis
Fmoc-Ile-OH

71989-23-6
475 suppliers
$6.00/5g

35737-15-6 Synthesis
Nalpha-FMOC-L-Tryptophan

35737-15-6
367 suppliers
$6.00/5g

91000-69-0 Synthesis
FMOC-L-Arginine

91000-69-0
226 suppliers
$6.00/1g

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Yield:-

Reaction Conditions:

Stage #1:Fmoc-L-Arg-OH with O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
Stage #2: with piperidine in N,N-dimethyl-formamide
Stage #3:Fmoc-Leu-OH;Fmoc-Pro-OH;Fmoc-Ile-OH;Fmoc-Trp-OH;Fmoc-Lys-OH;Fmoc-L-Arg-OHFurther stages;

References:

Libardo, M. Daben;Cervantes, Jorge L.;Salazar, Juan C.;Angeles-Boza, Alfredo M. [ChemMedChem,2014,vol. 9,# 8,p. 1892 - 1901]