ChemicalBook CAS DataBase List L-Alanine Isopropyl Ester Hydrochloride

L-Alanine Isopropyl Ester Hydrochloride synthesis

2synthesis methods

Product Name:L-Alanine Isopropyl Ester Hydrochloride
CAS Number:39825-33-7
Molecular formula:C6H13NO2
Molecular Weight:131.17

L-alanine isopropyl ester hydrochloride can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process. It can be synthesized by esterification of L-Alanine and Isopropyl alcohol.

56-41-7 Synthesis

56-41-7
766 suppliers
$5.00/5g

67-63-0 Synthesis

67-63-0
1541 suppliers
$16.00/25ML

39825-33-7
237 suppliers
$14.00/25g

Yield:39825-33-7 87%

Reaction Conditions:

with hydrogenchloride;thionyl chloride at 0 - 20;

Steps:

11.a (S)-isopropyl 2-aminopropanoate (I-11a)
SOCl2 (29 mL, 400 mmcl) was added dropwise at 0 °C to a suspension of the HCl salt of L-alanine (17.8 g, 200 mmcl) in isopropanol (700 mL). The suspension was stirred at roomtemperature over night, then concentrated, which gave the title compound (29.2 g, 87%).

References:

MEDIVIR AB;KALAYANOV, Genadiy;PINHO, Pedro;WESTERLIND, Hans;WIKTELIUS, Daniel;WÄHLING, Horst WO2015/56213, 2015, A1 Location in patent:Page/Page column 66

FullText

10065-72-2
20 suppliers
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67-63-0 Synthesis

67-63-0
1541 suppliers
$16.00/25ML

39825-33-7
237 suppliers
$14.00/25g

References

L-Alanine Isopropyl Ester Hydrochloride Related Search:

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