ChemicalBook CAS DataBase List L-Selenomethionine

L-Selenomethionine synthesis

5synthesis methods

Product Name:L-Selenomethionine
CAS Number:3211-76-5
Molecular formula:C5H11NO2Se
Molecular Weight:196.11

2185-03-7 Synthesis

2185-03-7
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3211-76-5
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Yield:99 % ee

Reaction Conditions:

in N,N-dimethyl-formamide; for 2 h;Inert atmosphere;Reflux;

Steps:

1.3

Under a nitrogen atmosphere, 13.75 g of α-amino-γ-butyrolactone hydrochloride was mixed with 40 mL of DMF,Stir evenly. 15.2 g of sodium methyl selenate was dissolved in 20 mL of DMF, added to the above system and refluxed for 2 h. After the reaction was completed, the pH of the system was adjusted to 6.0 with an aqueous acetic acid solution to give a white solid,Solid water and ethanol mixed solution recrystallization, both L-selenomethionine. The total yield was 72.11%Chemical purity> 99%, ee> 99%.

References:

CN106928110,2017,A Location in patent:Paragraph 0028; 0030

45172-44-9 Synthesis