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METHYL-[2-(4-METHYL-THIAZOL-5-YL)-ETHYL]-AMINE synthesis

2synthesis methods
-

Yield:55496-62-3 76%

Reaction Conditions:

Stage #1: 5-(2-methylsulfonyloxyethyl)-4-methylthiazole;methylamine in water;acetonitrile at 140; under 15514.9 Torr; for 0.166667 h;Flow reactor;
Stage #2: with potassium hydroxide in water;

References:

Lebel, Hélène;Mathieu, Gary;Patel, Heena [Organic Process Research and Development,2020,vol. 24,# 10,p. 2157 - 2168]