Methyl 4-forMylfuran-2-carboxylate synthesis
1synthesis methods
- Product Name:Methyl 4-forMylfuran-2-carboxylate
- CAS Number:1170719-56-8
- Molecular formula:C7H6O4
- Molecular Weight:154.12
Yield:1170719-56-8 34%
Reaction Conditions:
Stage #1: furan-3-carboxaldehydewith morpholine;n-butyllithium;sec.-butyllithium in tetrahydrofuran;hexane;cyclohexane at -78; for 2.5 h;Inert atmosphere;
Stage #2: methyl chloroformate in tetrahydrofuran;hexane;cyclohexane at -78 - 20; for 1.08333 h;Inert atmosphere;
References:
Wolter, Falko E.;Schneider, Kathrin;Davies, Brian P.;Socher, Elke R.;Nicholson, Graeme;Seitz, Oliver;Suessmuth, Roderich D. [Organic Letters,2009,vol. 11,# 13,p. 2804 - 2807] Location in patent:supporting information; experimental part