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ChemicalBook CAS DataBase List MPI_5a
1259296-46-2

MPI_5a synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / 1,2-dichloro-ethane / 0.08 h
1.2: 20 °C
2.1: hydroxylamine hydrochloride; potassium hydroxide / methanol / 2 h / 80 °C

References:

MILLENNIUM PHARMACEUTICALS, INC.;BLACKBURN, Christopher;CIAVARRI, Jeffrey;GIGSTAD, Kenneth;XU, He WO2010/151318, 2010, A1