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murocainide synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 90 percent / HCl / ethanol / 20 h / Heating
2: 89 percent / CHCl3 / 2 h / Ambient temperature
3: 60 percent / K2CO3 / acetonitrile / 4 h / Heating

References:

Bourgery, Guy;Dostert, Philippe;Lacour, Alain;Langlois, Michel;Pourrias, Bernard;Tisne-Versailles, Jacky [Journal of Medicinal Chemistry,1981,vol. 24,# 2,p. 159 - 167]

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