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ChemicalBook CAS DataBase List N-[3-(6-CHLORO-PYRAZIN-2-YL)-PHENYL]-ACETAMIDE
874143-25-6

N-[3-(6-CHLORO-PYRAZIN-2-YL)-PHENYL]-ACETAMIDE synthesis

1synthesis methods
4774-14-5 Synthesis
2,6-Dichloropyrazine

4774-14-5
350 suppliers
$5.00/1g

78887-39-5 Synthesis
3-Acetamidophenylboronic acid

78887-39-5
244 suppliers
$9.00/250mg

N-[3-(6-CHLORO-PYRAZIN-2-YL)-PHENYL]-ACETAMIDE

874143-25-6
10 suppliers
inquiry

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Yield:874143-25-6 54.7%

Reaction Conditions:

with PdCl2[1,3-bis(diphenylphosphino)propane]*CH2Cl2;sodium carbonate in 1,2-dimethoxyethane; for 5 h;Heating;Suzuki coupling;

References:

Niculescu-Duvaz, Ion;Roman, Esteban;Whittaker, Steven R.;Friedlos, Frank;Kirk, Ruth;Scanlon, Ian J.;Davies, Lawrence C.;Niculescu-Duvaz, Dan;Marais, Richard;Springer, Caroline J. [Journal of Medicinal Chemistry,2006,vol. 49,# 1,p. 407 - 416]

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