N-(cyclopropylmethyl)normorphine synthesis

2synthesis methods

Product Name:N-(cyclopropylmethyl)normorphine
CAS Number:1976-45-0
Molecular formula:C20H23NO3
Molecular Weight:325.4

57-27-2
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 48 percent / 1,8-diaminonaphthalene / 1,2-dichloro-ethane / 6 h / 65 °C
2: 63 percent / HBr / ethanol; diethyl ether / 8 h / 25 °C
3: NaHCO₃ / ethanol / 10 h / 80 °C

References:

Fang;Takemori;Portoghese [Journal of Medicinal Chemistry,1984,vol. 27,# 10,p. 1361 - 1363]

Morphinan-6-ol, 17-(cyclopropylmethyl)-7,8-didehydro-4,5-epoxy-3-methoxy-, (5α,6α)-

77794-51-5
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1976-45-0
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References

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