2-mercapto-N-methylbenzamide synthesis
- Product Name:2-mercapto-N-methylbenzamide
- CAS Number:20054-45-9
- Molecular formula:C8H9NOS
- Molecular Weight:167.23
1862-88-0
74 suppliers
$21.00/100mg
16420-13-6
293 suppliers
$5.00/5g
20054-45-9
168 suppliers
$172.00/250mg
Yield:20054-45-9 97.2%
Reaction Conditions:
with 1,4-diaza-bicyclo[2.2.2]octane in tetrahydrofuran at 40;Solvent;Reagent/catalyst;Temperature;
Steps:
1-9
Dissolve 30.23g (0.2mol) of 2-hydroxy-N-methylbenzamide in tetrahydrofuran (50ml),Slowly add 29.66g (0.24mol) of dimethylaminothioformyl chlorideAnd 31.39g (0.28mol) triethylenediamine,The temperature is controlled at 40°C for the reaction, and after the reaction is detected by TLC,Add ethyl acetate and purified water (V ethyl acetate: V purified water = 3:1) 40ml,Concentrate the organic layer under reduced pressure to obtain 2-mercapto-N-methylbenzamide,The yield is 97.2%, and the HPLC purity is 99.95%.
References:
CN112209861,2021,A Location in patent:Paragraph 0040-0057
![2,2'-dithiobis[N-methylbenzamide]](/CAS/GIF/2527-58-4.gif)
2527-58-4
108 suppliers
$75.00/2g
20054-45-9
168 suppliers
$172.00/250mg
593-51-1
561 suppliers
$21.00/100g
4892-02-8
151 suppliers
$23.00/1g
20054-45-9
168 suppliers
$172.00/250mg
119-80-2
435 suppliers
$7.00/25g
20054-45-9
168 suppliers
$172.00/250mg
![Benzamide, N-methyl-2-[(phenylmethyl)sulfinyl]-](/CAS/20210305/GIF/54705-26-9.gif)
54705-26-9
0 suppliers
inquiry
20054-45-9
168 suppliers
$172.00/250mg