N,N-dimethyl-4-Piperidinesulfonamide synthesis

2synthesis methods

Product Name:N,N-dimethyl-4-Piperidinesulfonamide
CAS Number:956075-49-3
Molecular formula:C7H16N2O2S
Molecular Weight:192.28

4-[(dimethylamino)sulfonyl]-1-Piperidinecarboxylic acid phenylmethyl ester

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956075-49-3
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Yield:956075-49-3 906 mg

Reaction Conditions:

with 10% Pd/C;hydrogen in tetrahydrofuran;methanol at 20; under 760.051 Torr; for 2 h;

Steps:

65.2

(2) To a solution of Compound 2 (1.57 g) in methanol (5 mL)/tetrahydrofuran (20 mL) was added 10% palladium carbon (wetted with ca. 50% water, 300 mg), and the mixture was stirred under hydrogen atmosphere (1 atm) at room temperature for 2 hours. Palladium carbon was removed by filtration, and then the filtrate was concentrated under reduced pressure to give Compound 3 (906 mg) as a colorless powder. MS (APCI): m/z 193 [M+H]+

References:

EP3150578,2017,A1 Location in patent:Paragraph 0595

287953-54-2 Synthesis

N-BENZYLOXYCARBONYL-4-PIPERIDINESULFONYL CHLORIDE

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956075-49-3
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References