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ChemicalBook CAS DataBase List N5-Acetyl-N2-Fmoc-L-Ornithine

N5-Acetyl-N2-Fmoc-L-Ornithine synthesis

2synthesis methods
109425-55-0 Synthesis
Fmoc-Orn(Boc)-OH

109425-55-0
307 suppliers
$8.00/1g

N5-Acetyl-N2-Fmoc-L-Ornithine

172690-48-1
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: caesium carbonate / N,N-dimethyl-formamide / 3 h / 20 °C
2: 0.33 h / 20 °C
3: triethylamine / dichloromethane / 2 h / 0 - 20 °C
4: tetrakis(triphenylphosphine) palladium(0); morpholine / tetrahydrofuran / 0.33 h / 20 °C / Inert atmosphere

References:

Pedersen, Søren W.;Moran, Griffin E.;Sereikaitė, Vita;Haugaard-Kedström, Linda M.;Strømgaard, Kristian [ChemBioChem,2016,vol. 17,# 20,p. 1936 - 1944]