Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List naphthalen-2-ylmethyl acetate
35480-23-0

naphthalen-2-ylmethyl acetate synthesis

13synthesis methods
-

Yield:35480-23-0 99%

Reaction Conditions:

with CH3O3S(1-)*C27H53N2O12(1+) in acetonitrile at 90; for 0.5 h;

Steps:

4.23. General procedure for SN2 reaction

General procedure: MNu (M=KOAc, KSAc, NaN3 or KCN) (3.0 mmol) was added to a mixture of each mesylate, triflate or bromide compound (1.0 mmol), [dihexaEGim][OMs] (346 mg, 0.5 mmol) and acetonitrile (4 mL) in a reaction vial. The reaction mixture was stirred over 0.5-3 h at 90 °C. The reaction mixture was filtered and washed with diethyl ether (15 mL). The filtrate was evaporated under reduced pressure. Flash column chromatography (10% EtOAc/hexanes) of the filtrate afforded each product compound.

References:

Jadhav, Vinod H.;Kim, Ju-Young;Chi, Dae Yoon;Lee, Sungyul;Kim, Dong Wook [Tetrahedron,2014,vol. 70,# 2,p. 533 - 542]