ChemicalBook CAS DataBase List PENTADECANOIC ACID

PENTADECANOIC ACID synthesis

9synthesis methods

Product Name:PENTADECANOIC ACID
CAS Number:1002-84-2
Molecular formula:C15H30O2
Molecular Weight:242.4

106-02-5 Synthesis

106-02-5
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$20.00/1g

1002-84-2
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$17.00/5g

Yield:1002-84-2 71%

Reaction Conditions:

with palladium 10% on activated carbon;W(OTf)₆;hydrogen at 135; under 760.051 Torr; for 12 h;

Steps:

31 Preparation of N-Pentadecanoic acid by Pentadecanolide

General procedure: Specific methods are as follows: propiolactone was added (0.36g, 5mmol), palladium on carbon (10%, 26.5mg, 0.025mmol, 0.5mol%) in the reactor and W (OTf)₆(107.8mg, 0.1mmol, 2mol%). A hydrogen balloon connected to the top of the reactor, and the reactor was purged with hydrogen gas atmosphere. Hydrogen atmosphere at normal pressure, the reaction was stirred at 135 deg.] C after 12h, detected by gas, γ- valerolactone complete conversion of starting material, and only n-valeric acid. The method carried out as follows completion of the hydrogenation reaction of the ring-opening reaction system separation, to obtain the desired product n-valeric acid: The reaction was completed reaction mixture was dissolved with methylene chloride, filtered to remove the palladium on carbon catalyst and W (OTf)₆99% yield measured propionic acid, purity of the product was 99%. NMR data for the product using the embodiment of the present invention is the NMR identified the product as follows:The specific reaction procedure and the operation method were the same as in Example 27, and the yield was 71%, and the purity of the product was 99%. The product was subjected to nuclear magnetic identification using the manner described in the present invention, and the NMR data of the product were as follows:

References:

CN106831389,2017,A Location in patent:Paragraph 0113; 0131-0133

629-73-2 Synthesis