Phosphorane, triphenyldithiocyanato- synthesis
1synthesis methods
- Product Name:Phosphorane, triphenyldithiocyanato-
- CAS Number:66365-41-1
- Molecular formula:C20H15N2PS2
- Molecular Weight:378.4503
Yield:-
Reaction Conditions:
Stage #1: triphenylphosphinewith bromine in dichloromethane;
Stage #2: lead(II) thiocyanate in dichloromethane;
Steps:
General procedure A: synthesis of 6-bromo, 8- bromo, and 8-bromo-6-chloro-1,3-benzoxazines 11-13
Triphenylphosphine (6mmol) is added to dry DCM (20mL) then bromine (6.30mmol) is slowly added. Lead thiocyanate (7.50mmol) was added with dry DCM (40mL) to the above mixture according to the previously reported procedure [21]
References:
Morrison, Rick;Al-Rawi, Jasim M.A.;Jennings, Ian G.;Thompson, Philip E.;Angove, Michael J. [European Journal of Medicinal Chemistry,2016,vol. 110,p. 326 - 339]