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ChemicalBook CAS DataBase List Pimavanserin
107456-06-4

Pimavanserin synthesis

4synthesis methods
1003-99-2 Synthesis
2-Bromo-5-fluoroaniline

1003-99-2
317 suppliers
$6.00/5g

Pimavanserin

107456-06-4
12 suppliers
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Yield:107456-06-4 100 %

Reaction Conditions:

Stage #1: 4-aminomethylphenol;4-hydroxy-benzaldehydewith sodium sulfate in methanol;Inert atmosphere;Reflux;
Stage #2: with sodium tetrahydroborate in tetrahydrofuran;methanol at 20;Inert atmosphere;

References:

Di Noja, Simone;Garrido, Marina;Gualandi, Lorenzo;Ragazzon, Giulio [Chemistry - A European Journal,2023] Location in patent:supporting information

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