(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol synthesis
- Product Name:(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol
- CAS Number:243640-19-9
- Molecular formula:C14H21NO3
- Molecular Weight:251.32
139290-72-5
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243640-19-9
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Yield:78 % ee
Reaction Conditions:
with bis(1,5-cyclooctadiene)diiridium(I) dichloride;potassium tert-butylate;hydrogen;isopropyl alcohol;(1R,2R)-N-(2-diphenylphosphanylbenzyl)cyclohexane-1,2-diamine in tert-butyl alcohol at 50; under 37503.8 Torr; for 25 h;Catalytic behavior;Autoclave;Schlenk technique;Overall yield = 68 %; enantioselective reaction;Temperature;
References:
Fuentes, Jose A.;Carpenter, Ian;Kann, Nina;Clarke, Matthew L. [Chemical Communications,2013,vol. 49,# 87,p. 10245 - 10247] Location in patent:supporting information
50583-51-2
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243640-19-9
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$165.00/2.5mg
139290-71-4
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243640-19-9
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140235-25-2
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243640-19-9
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$165.00/2.5mg
139290-72-5
3 suppliers
inquiry
243640-19-9
9 suppliers
$165.00/2.5mg