(R)-2-AMino-2-(3,5-difluorophenyl)ethanol synthesis
- Product Name:(R)-2-AMino-2-(3,5-difluorophenyl)ethanol
- CAS Number:957121-38-9
- Molecular formula:C8H9F2NO
- Molecular Weight:173.16
![2-Oxazolidinone, 3-[2-(3,5-difluorophenyl)acetyl]-4-(phenylmethyl)-, (4R)-](/CAS/20210305/GIF/1589473-76-6.gif)
1589473-76-6
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957121-38-9
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$45.00/5mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: potassium hexamethylsilazane / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
1.2: 0.17 h / -78 °C / Inert atmosphere
2.1: lithium borohydride; water / tetrahydrofuran / 24.5 h / 0 - 20 °C
3.1: palladium 10% on activated carbon; hydrogen / methanol / 4 h / Inert atmosphere
References:
Chen, Chia-Yu;Liao, Yung-Feng;Chang, Ming-Yun;Hu, Ming-Kuan [Archiv der Pharmazie,2014,vol. 347,# 3,p. 161 - 173]
105184-38-1
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957121-38-9
27 suppliers
$45.00/5mg