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ChemicalBook CAS DataBase List (S)-3-HYDROXY-PYRROLIDIN-2-ONE
34368-52-0

(S)-3-HYDROXY-PYRROLIDIN-2-ONE synthesis

4synthesis methods
-

Yield:34368-52-0 75%

Reaction Conditions:

Stage #1: (S)-4-azido-2-hydroxybutyric acid ethyl esterwith triphenylphosphine in tetrahydrofuran at 20; for 6 h;
Stage #2: with water in tetrahydrofuran at 20; for 48 h;

References:

Huang, Pei-Qiang;Zheng, Xiao;Wei, Hua [Heterocycles,2003,vol. 60,# 8,p. 1833 - 1841]