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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
62624-45-7

(S)-4-PHENYLPYRROLIDIN-2-ONE synthesis

9synthesis methods
3-Pyrrolidinecarboxylic acid, 2-oxo-4-phenyl-, ethyl ester, (4S)-

252338-34-4
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(S)-4-PHENYLPYRROLIDIN-2-ONE

62624-45-7
15 suppliers
$45.00/2.5mg

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Yield:62624-45-7 94%

Reaction Conditions:

Stage #1: ethyl 2-pyrrolidinone-3-carboxylatewith sodium hydroxide in ethanol;saponification;
Stage #2: with toluene-4-sulfonic acidDecarboxylation;

References:

Ji, Jianguo;Barnes, David M.;Zhang, Ji;King, Steven A.;Wittenberger, Steven J.;Morton, Howard E. [Journal of the American Chemical Society,1999,vol. 121,# 43,p. 10215 - 10216]

Benzenepropanoic acid, β-(aminomethyl)-, ethyl ester, (βS)-

1431854-83-9
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(S)-4-PHENYLPYRROLIDIN-2-ONE

62624-45-7
15 suppliers
$45.00/2.5mg

References
2H-Pyrrol-2-one, 1,5-dihydro-4-phenyl-

92119-61-4
4 suppliers
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71657-88-0 Synthesis
(R)-4-Phenylpyrrolidin-2-one

71657-88-0
13 suppliers
$844.00/1g

(S)-4-PHENYLPYRROLIDIN-2-ONE

62624-45-7
15 suppliers
$45.00/2.5mg

References
5153-67-3 Synthesis
(E)-2-Nitroethenylbenzene

5153-67-3
140 suppliers
$6.00/1g

(S)-4-PHENYLPYRROLIDIN-2-ONE

62624-45-7
15 suppliers
$45.00/2.5mg

References
Propanedioic acid, 2-[(1S)-2-nitro-1-phenylethyl]-, 1,3-diethyl ester

252338-27-5
0 suppliers
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(S)-4-PHENYLPYRROLIDIN-2-ONE

62624-45-7
15 suppliers
$45.00/2.5mg

References