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ChemicalBook CAS DataBase List (S)-tert-butyl 2-vinylpyrrolidine-1-carboxylate
115393-77-6

(S)-tert-butyl 2-vinylpyrrolidine-1-carboxylate synthesis

10synthesis methods
69610-41-9 Synthesis
N-BOC-L-Prolinal

69610-41-9
261 suppliers
$9.00/1g

(S)-tert-butyl 2-vinylpyrrolidine-1-carboxylate

115393-77-6
24 suppliers
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Yield:115393-77-6 97%

Reaction Conditions:

Stage #1: methyl-triphenylphosphonium iodidewith potassium tert-butylate in diethyl ether at 20; for 2 h;Inert atmosphere;
Stage #2: Boc-L-Pro-H in diethyl ether;Inert atmosphere;

References:

Rong, Hao-Jie;Cheng, Yong-Feng;Liu, Fan-Fan;Ren, Shu-Jian;Qu, Jin [Journal of Organic Chemistry,2017,vol. 82,# 1,p. 532 - 540]