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ChemicalBook CAS DataBase List SF2523
1174428-47-7

SF2523 synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1 h / 0 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: trifluoromethylsulfonic anhydride / dichloromethane / 20 °C
3.1: caesium carbonate; tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 0.25 h / 130 °C / Microwave irradiation

References:

Morales, Guillermo A.;Garlich, Joseph R.;Su, Jingdong;Peng, Xiaodong;Newblom, Jessica;Weber, Kevin;Durden, Donald L. [Journal of Medicinal Chemistry,2013,vol. 56,# 5,p. 1922 - 1939]