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ChemicalBook CAS DataBase List Taladafil impurity
1356345-67-9

Taladafil impurity synthesis

2synthesis methods
Taladafil impurity

1356345-67-9
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: trifluoroacetic acid / dichloromethane / 0 - 20 °C / Molecular sieve
2: triethylamine / chloroform / -10 - 20 °C
3: ethanol / Reflux

References:

Beghyn, Terence B.;Charton, Julie;Leroux, Florence;Henninot, Antoine;Reboule, Irena;Cos, Paul;Maes, Louis;Deprez, Benoit [Journal of Medicinal Chemistry,2012,vol. 55,# 3,p. 1274 - 1286]

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