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100445-98-5

Tetrahydro-1H-pyrrolizin-7a(5H)-ylacetyl chloride synthesis

5synthesis methods
20463-30-3 Synthesis
1H-Pyrrolizine, 2,3,5,6-tetrahydro-

20463-30-3
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 66 percent / dioxane / 14 h / Heating
2: oxalyl chloride / CHCl3 / 1 h / 40 °C

References:

Miyano, Seiji;Sumoto, Kunihiro;Satoh, Fumio;Shima, Keiyu;Hayashimatsu, Mariko;et al. [Journal of Medicinal Chemistry,1985,vol. 28,# 6,p. 714 - 717]